Understanding Recurrent Implantation Failure (RIF)
What is RIF?
Defined as failure to achieve pregnancy after three or more IVF cycles with transfer of good-quality embryos.
Distinct from recurrent miscarriage; RIF refers specifically to embryos failing to implant, not pregnancy loss
Common Causes of RIF
Embryo quality/genetic issues (aneuploidy).
Uterine factors: structural anomalies, thin lining, fibroids/polyps.
Endometrial receptivity issues, including immune dysregulation.
Hormonal imbalances, thyroid or progesterone insufficiency .
